Sky TV pundit Alan Brazil has stuck his neck out and tipped Manchester City to beat Colchester in the pay-per-view clash.
Brazil last watched the U's at Layer Road in November when they drew 1-1 with Macclesfield.
The former Ipswich, Manchester United and Scotland striker, said: "Manchester City are a very tough proposition. They are definites for the play-offs, and I think they will have the edge over Colchester.
"But coming to Layer Road and it's tight pitch will be difficult and will be a test for City.
"For Colchester to win they need to battle, especially in midfield which will be the key. I have been impressed with David Gregory and David Greene this season.
"Gregory has scored a lot of goals, especially from the spot and City will need to keep an eye on him."
Brazil, who will be at the ground working for the Sky commentary team revealed he is a fan of Friday night football at Layer Road.
He said: "I used to come down a lot when I was at Ipswich and still do when I can. Friday nights are great fun with a great atmosphere and maybe Saturday evening will be the same."
Manchester City manager Joe Royle has dismissed rumours he is set to move for former Ipswich Town striker Alex Mathie who is now at Dundee United.
Reports claimed that Royle was looking to sign the 30-year-old former Celtic, Newcastle and Ipswich forward on loan or possibly in a player exchange deal but the Sky Blues boss ruled out the speculation.
Mathie has struggled to fit in at Dundee United following his move from Ipswich and Tannadice boss Paul Sturrock is looking to sell the striker - but not to City apparently.
Royle is looking to strengthen his attack, maybe even before this weekend with Shaun Goater out with a shoulder injury and Gareth Taylor doubtful with a thigh strain. If the strike pairing are ruled out for the Layer Road clash, and assuming that a striker doesn't arrive on loan, then Paul Dickov and Danny Allsopp will start up front as a pairing for only the second time this season.
Converted for the new archive on 19 November 2001. Some images and formatting may have been lost in the conversion.
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